Organodilithium Intermediates as Useful Dianionic Synthons: Recent Advances

Abstract

This review will update the use of organodilithium intermediates in synthetic organic chemistry, paying special attention to their use in carbon-carbon bond forming reactions, in which two equal or different electrophiles are introduced (at once or in a two-step process) in the structure of the starting material. This methodology allows the generation of polyfunctionalized organic molecules in a very direct manner through only one synthetic operation: tandem lithiation-reaction with electrophiles.