Organocatalytic asymmetric conjugate addition of t-butyl nitroacetate to o-quinone methides: synthesis of optically active α-nitro-β,β-diaryl-propionates

Abstract

α-Nitro-β,β-diaryl-propionates were prepared with good yields and excellent enantioselectivities via asymmetric conjugate addition of t-butyl nitroacetate to in situ generated o-quinone methides.