Organo‐Cascade Catalysis: Application of Merged Iminium‐Enamine Activation Technique and Related Cascade Reactivities

Abstract

AbstractIminium‐enamine catalyzed chemical reactions provide a blueprint to carry out diverse organocatalyzed cascade reactions with high selectivity and efficiency and therefore, this class of reactions holds a great promise to offer important synthetic strategies to deliver valuable and useful natural products as well as biologically potent compounds with immense significance. The applications of enamine‐iminium (EN‐IM) catalysis in organocatalytic cascade reactions become a very useful strategy in organic synthesis. This review article aims to focus on an important overview about different strategies employed in the production of value added organic products. An effort has also been made to demonstrate the applications of merged Iminium‐enamine activation techniques in proceeding organo‐cascade reactions to illuminate the advantage of atom economy and step economy in the chemical reactions.