Organic Reaction Schemes and General Reaction — Matrix Types, I Rearrangement Reactions

Abstract

A sample consisting of about 120 organic rearrangement reactions has been quantified in terms general reaction matrices R̃ expressing electron-flow processes. About two thirds of the reactions considered conform to only two distinct R̃-matrices, 80% to five such schemes. The frequency distribution is qualitatively similar to that found for larger, more randomly chosen, sets of organic reactions. Examples of the various electron-flow processes are given. The bearings of the results on synthesis-planning are discussed.