Organic Carbon-Heteroatom Cross-Coupling Reactions Mediated by Supported Transition Metal-Based Catalysts

Abstract

<div>Organic cross-coupling reactions have been broadly utilized in the synthesis</div><div>of various organic products and valuable compounds. It is considered the backbone for</div><div>the synthesis of various medicinally significant compounds. Although numerous</div><div>organic compounds are made out of C-C bonds, however, the presence of heteroatoms,</div><div>like nitrogen, oxygen and sulfur, makes them utilitarian. Conductive polymers and</div><div>drugs often contain amine C-N bonds, and practically, the majority of natural products</div><div>contain ether, ketone, or ester C-O bonds. Heterocyclic compounds containing C-N, CO,</div><div>or C-S bonds in the ring structure are found in all applications of chemistry. As a</div><div>result of the developing significance of these cross-coupling reactions, the advancement</div><div>of new extemporized strategies for the synthesis of such items has become the</div><div>most elevated need for some researchers. Researchers are zeroing in on the advancement</div><div>of green synthetic methods for the synthesis of such compounds. Catalysis is</div><div>steadily overwhelming in the field of synthesis because of the expanding capacity to</div><div>plan new materials with improved synergist exhibitions. Catalysis is proclaimed as a</div><div>more up-to-date process that shows stability, durability, higher activity, and cost</div><div>viability analysis. High-yielding cross-coupling reactions using supported catalysts are</div><div>also reported, resulting in the development of a large number of very effective catalysts</div><div>for organic cross cross-coupling processes.. Heterogeneous catalysis has the advantage</div><div>of easy separation and compared to homogeneous catalysis, product isolation requires</div><div>less amount of the solvent. However, sometimes there may be a compromise in the</div><div>selectivity process. This chapter contains a detailed discussion on different carbonheteroatom</div><div>cross-coupling reactions mediated by supported transition metal-based</div><div>catalysts. The scope of these cross-coupling reactions in the pharmaceutical and</div><div>industrial sectors has been investigated. Exceptional methodologies and significant</div><div>advances accomplished in the field of carbon-heteroatom cross-coupling reactions have</div><div>been talked about.</div>