Abstract

The splanchnic nerves of toads were tightly ligated and the organelles present both on the proximal and the distal side of the constriction were counted after zero, 24 and 48 hrs. Swelling of the fibers and accumulation of mitochondria and of smooth canaliculi were found to be the most conspicuous expressions of damming in the nerve segments above the constriction. No changes in the microtubule population or in the ratio of dense-core microtubules to empty microtubules were observed. A progressive collection of granulated vesicles is described for a minority of fibers in the segment proximal to the ligature. Evidence is presented in support of the view that such granulated vesicles are budded from swollen canaliculi. Fine structural expressions of damming were not found in the nerve segments distal to the constriction.

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