Abstract

One of the major challenges in nanomedicine is to develop nanoparticulate systems able to serve as efficient diagnostic

Highlights

  • One of the major challenges in nanomedicine is to develop nanoparticulate systems able to serve as efficient diagnostic, therapeutic or theragnostic tools against severe diseases, such as infectious or neurodegenerative disorders [1]

  • One way to achieve it, is to develop an innovative approach based on organ on chip (OOC) devices for the evaluation and the enhancement of the therapeutic efficiency of smart nano-object

  • It is worth to mention that superparamagnetic iron oxide nanoparticles (SPIONs) are already approved by the US Food and Drug Administration (FDA) and by the European Union [4] and have been greatly investigated due to their good biocompatibility, low toxicity and ease of synthesis [6]

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Summary

Introduction

One of the major challenges in nanomedicine is to develop nanoparticulate systems able to serve as efficient diagnostic, therapeutic or theragnostic tools against severe diseases, such as infectious or neurodegenerative disorders [1]. One way to achieve it, is to develop an innovative approach based on organ on chip (OOC) devices for the evaluation and the enhancement of the therapeutic efficiency of smart nano-object. Development of targeting drug nano carrier for cancer therapy/theragnostic

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