Ordered self-assembly of screen-printed flower-like CuO and CuO/MWCNTs modified graphite electrodes and applications in non-enzymatic glucose sensor

Abstract

Two non-enzymatic glucose sensors based on ordered self-assembly of flower-like CuO and CuO/MWCNTs modified graphite electrodes have been successfully fabricated by a facile and effective screen-printed way. The prepared flower-like CuO and CuO/MWCNTs were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray diffraction (XRD). The cyclic voltammetry (CV) and chronoamperometry demonstrated that the CuO/MWCNTs modified electrode displayed much higher electrocatalytic activity than the CuO modified electrode toward glucose, exhibiting a high sensitivity of 1.211mAmM−1cm−2, a fast response time of 3s, a low detection limit of 4μM (S/N=3) and three linear regions from 4μM to 14.5mM. The sensors can effectively resist the effect of interferences such as UA, DA, AA, fructose, lactose, sucrose and NaCl. In addition, the results tested by real blood serum samples showed that the optimized electrodes were applicable for determination of glucose in real blood serum samples. Thus, the CuO and CuO/MWCNTs modified electrodes are potential candidates for routine glucose analysis.