Abstract

Primary metabolic pathways contribute the necessary components for plant life, but they also produce precursors that are consumed for secondary metabolite biosynthesis. Secondary metabolites are non-essential but confer predator and stress protection, increasing plants’ fitness; the regulation of their biosynthesis is not well understood, but some are accumulated by (methyl)jasmonate (MeJA), a stress response plant hormone. One class of secondary metabolites, the terpenoid indole alkaloids (TIAs), originates from the tryptophan biosynthetic pathway and is activated by exogenous MeJA. Tryptophan acts as a primary metabolite precursor in TIA secondary metabolite biosynthesis, but little is understood about how the primary and secondary metabolism pathways are coordinated.

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