Orbital non-hodgkin’s lymphoma with systemic spread – interesting case reports

Abstract

Primary Non Hodgkin’s lymphoma (NHL) of orbit is rare, representing 8-10% of extranodal NHLs and 1% of all NHLs. Of these, High grade lymphomas have an aggressive course and early propensity for systemic spread despite early aggressive treatment.We report 2 cases of Orbital NHL who presented initially with Unilateral upper lid mass, and bilateral proptosis which on further evaluation were diagnosed to have Orbital NHL with tissue biopsy showing Diffuse Large B cell lymphoma in one and mixed variety in other respectively. They were started on chemotherapy. Our first patient defaulted after 4 cycles and came later with inguinal and axillary lymphadenopathy and painful arm swellings. Second patient received 10 cycles of chemotherapy but he developed diffuse Lymphadenopathy and hepatosplenomegaly. In both the cases only palliative care could be offered.