Abstract

Lymphomas are known as neoplasm’s caused by clone proliferation of B and T lymphocytes. Extranodal lymphoma arises from tissues other than lymph nodes or even from sites which normally doesn’t contain lymph tissues. Orbital adnexal lymphoma arises from eyelid, orbit, lacrimal glands or conjunctivae and it is totally different from intraocular lymphoma. Wide range of differential diagnosis including infectious inflammatory orbital disease, preseptal and orbital cellulitis, orbital idiopathic inflammatory disease-pseudotumors, especially dacryoadenitis and myositis and thyroid associate orbit disease makes the diagnosis of orbital adnexal lymphoma even more difficult. We represent the case of diagnostic delay of very aggressive form orbital non-Hodgkin lymphoma occurred because of the unspecific signs and symptoms as well as not indicative imaging investigation and laboratory tests.

Highlights

  • Lymphomas are known as neoplasm’s caused by clone proliferation of B and T lymphocytes

  • Orbital adnexal lymphoma arises from eyelid, orbit, lacrimal glands or conjunctivae and it is totally different from intraocular lymphoma

  • Wide range of differential diagnosis including infectious inflammatory orbital disease, preseptal and orbital cellulitis, orbital idiopathic inflammatory disease-pseudotumors, especially dacryoadenitis and myositis and thyroid associate orbit disease makes the diagnosis of orbital adnexal lymphoma even more difficult

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Summary

Introduction

Lymphomas are known as neoplasm’s caused by clone proliferation of B and T lymphocytes. In non-Hodgkin orbital lymphoma, MALT tumors are more common than DLBCL [8]. Sign and symptoms can vary depending on the site of the orbit. They are presented as an orbital palpebral mass, initially painless proptosis, with or without motility limitations, tearing and chemosis. Especially when it arises in the posterior orbit or it has muscular involvement, visual impairment, optic nerve compression and motility limitations can manifest [9] [10]. Differential diagnosis includes infectious inflammatory orbital disease, preseptal and orbital cellulitis, orbital idiopathic inflammatory disease-pseudotumors, especially dacryoadenitis and myositis and thyroid associate orbit disease. We represent the case of diagnostic delay of very aggressive form orbital non-Hodgkin lymphoma occurred because of the unspecific signs and symptoms as well as not indicative imaging investigation and laboratory tests. The purpose is to emphasize the importance of the early biopsy for the better and faster therapeutic and prognostic results

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