Orally Dispersible films a new platform for Drug Delivery System

Abstract

Orodispersible films are thin films, when in contact with saliva gets rapidly disintegrate and dissolve to release the medication for oral mucosal absorption. The film plays a major alternative approach to conventional oral dosage form like tablets, capsule, syrups. The thin films are considered to be convenient to swallow,self-administrable, rapid disintegration, dissolution and quick onset of effect which make it as a versatile platform for effective drug delivery. Oral disintegrating films have superiority over the tablet formulations because there is no risk of chocking and friability. Compared with the traditional dosage forms this dosage forms give greater advantage as it provides a new way for the pediatrics, geriatrics, bedridden patients etc. Several types of approaches are there for preparation of the films. Mostly solvent casting method is used for the development of orodispersible films. For the development of dosage forms polymers and plasticizers along with other excipients are used. Usually hydrophilic polymers are used for the preparation. The design of the film requires comprehensive knowledge of pharmaceutical and pharmacological properties of drug and polymers along with the manufacturing therefore the aim of the review provide an overview of preparation the film The present review focus on benefit, composition, approaches for formulation and evaluation of the Orally dispersible film.