Abstract
White sponge nevus is an autosomal dominant skin disorder characterized by white, irregular, diffuse plaques mainly affecting the oral mucosa. Histological findings of white sponge nevus are characteristic but not pathognomonic. We report a case of an oral white sponge nevus in a 6-year-old girl, which poses a problem in differential diagnosis with oral candidiasis. No treatment was performed because of the benign and asymptomatic nature of the lesions.
Highlights
White sponge nevus is a rare hereditary mucosal disorder characterized by asymptomatic spongy white plaques that affect oral mucosa and less frequently nasal, esophageal, rectal, and genial mucosa
White sponge nevus is an autosomal dominant genodermatosis that is often manifested in early childhood and showed no gender preference [2]
No similar lesions were found in parents or in siblings. e mutations concern the Keratin 4 or Keratin 13 genes, encoding mucosa-specific keratin intermediate filament proteins Keratin 4 and Keratin 13, “respectively,” that are important for the assembly of keratin
Summary
White sponge nevus is a rare hereditary mucosal disorder characterized by asymptomatic spongy white plaques that affect oral mucosa and less frequently nasal, esophageal, rectal, and genial mucosa. Oral white sponge nevus appears as white or gray diffuse plaques thickened with multiple furrows and spongy texture located onbuccal, labial, gingival mucosa and floor of the mouth [1]
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