Abstract

The oral cavity is the most common extragenital site of infection. Oral lesions in secondary stage syphilis are particularly common when associated with general symptoms and cutaneous eruption. However, the exclusive oral localization, not associated with general manifestations, is uncommon. We report a case of a 27 year old male patient with isolated oral ulceration as the sole presentation of secondary syphilis. In contrast with the oral lesion of primary syphilis, which tends to be solitary, painless, indurated ulcers, oral lesions of secondary syphilis are typically painful, multiple and accompanied by a concomitant cutaneous eruption.

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