Abstract

Oral squamous papilloma is a benign proliferation of the flat stratified epithelium that has the exophytic papillary verrucous tumor as a consequence, induced by human papillomavirus. A 59-year-old female patient without risk factors had a lesion with an evolution of 3 months. On intraoral examination, we observed a single papular lesion with normochromic coloration, smooth surface, clear borders and oval shape, sessile base, and painful sensation located on the back of the tongue. An excisional biopsy was performed, and the diagnostic hypothesis was oral squamous papilloma. The histologic slices revealed fragments of mucosa exhibiting hyperplastic epithelium without atypia with slight koilocytes in the spiny layer and digitiform projections presenting islands of connective tissue in its interior. The microscope slide was fibrous and exhibited a discrete chronic inflammatory infiltrate. The diagnosis was compatible with oral squamous papilloma as well as the diagnosis hypothesis. After total removal of lesion, there was no recurrence. Oral squamous papilloma is a benign proliferation of the flat stratified epithelium that has the exophytic papillary verrucous tumor as a consequence, induced by human papillomavirus. A 59-year-old female patient without risk factors had a lesion with an evolution of 3 months. On intraoral examination, we observed a single papular lesion with normochromic coloration, smooth surface, clear borders and oval shape, sessile base, and painful sensation located on the back of the tongue. An excisional biopsy was performed, and the diagnostic hypothesis was oral squamous papilloma. The histologic slices revealed fragments of mucosa exhibiting hyperplastic epithelium without atypia with slight koilocytes in the spiny layer and digitiform projections presenting islands of connective tissue in its interior. The microscope slide was fibrous and exhibited a discrete chronic inflammatory infiltrate. The diagnosis was compatible with oral squamous papilloma as well as the diagnosis hypothesis. After total removal of lesion, there was no recurrence.

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