Abstract
Only a few studies have evaluated the clinicopathological features of oral squamous cell carcinoma (SCC) in Brazil, and most were conducted in the most industrialized region of the country, i.e. the southeastern region. The aim of this study was to evaluate the clinicopathological features of this malignant neoplasm in northeastern Brazil. Retrospective study performed in an oral pathology laboratory in Recife, Brazil. All cases of oral SCC that occurred between 2000 and 2015 were studied. Clinical data were recorded and histological slides were reviewed. Statistical analysis was performed using the chi-square test (P ≤ 0.05). A total of 194 cases were evaluated. The male-to-female ratio was 1.5:1. The mean age was 65.4 years, and only 6.6% of the cases occurred in patients younger than 41 years. Most tumors consisted of well-differentiated SCC (54.6%). The findings of this study highlight the higher prevalence of oral SCC among women and the increasing number of cases among young patients. Thus there is no specific risk group for oral SCC, as in the past. This fact needs to be taken into consideration in clinical routine care, so that apparently innocuous malignant lesions do not go unnoticed in these individuals.
Highlights
Squamous cell carcinoma (SCC) is a well-recognized malignant neoplasm that is responsible for more than 90% of oral malignancies.[1,2,3,4] Worldwide, 405,000 new cases of oral cancer are expected every year.[3]
All cases of squamous cell carcinoma that were diagnosed in the Oral Pathology Laboratory of the Federal University of Pernambuco, Recife, Brazil, between 2000 and 2015, were included in the study
Out of the 4,727 oral lesions diagnosed over a 15-year period, 250 were malignant (5.28%)
Summary
Squamous cell carcinoma (SCC) is a well-recognized malignant neoplasm that is responsible for more than 90% of oral malignancies.[1,2,3,4] Worldwide, 405,000 new cases of oral cancer are expected every year.[3] It is the seventh most common type of cancer among Brazilians.[5]. The etiology of these tumors is multifactorial. This fact needs to be taken into consideration in clinical routine care, so that apparently innocuous malignant lesions do not go unnoticed in these individuals
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