Artificial Organs | VOL. 47
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Oral sorbents for small, charged uremic toxins, and carbon block for regeneration of dialysate: Fourth down and long

Publication Date Nov 21, 2022

Abstract

Complexities of sorbent regeneration of dialysate led me to look at other ways to use sorbents to remove uremic toxins. An oral sorbent containing cation and anion exchangers showed effective binding of potassium, phosphate, sodium, hydrogen, and ammonium (from urea) in vitro. Animal studies are ongoing. Carbon block columns can effectively bind organic and middle molecules toxins from the dialysate. Together, these two technologies have the potential to greatly simplify dialysis for end-stage renal disease patients.

Concepts

Regeneration Of Dialysate Oral Sorbent Carbon Block Uremic Toxins Binding Of Ammonium Binding Of Sodium Binding Of Hydrogen Organic Toxins Binding Of Phosphate Animal Studies

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