Oral, Pharyngeal and Laryngeal Lesions in Mucous Membrane Pemphigoid and Usefulness of Narrow Band Imaging

Abstract

Mucous membrane pemphigoid is a relatively rare disorder involving mucosal lesions. Here, we report two cases of mucous membrane pemphigoid. This report is the first to discuss narrow band imaging of the mucosal features of mucous membrane pemphigoid. The two patients presented with sore throat and multiple stomatitis. Optic fiberscopy revealed mucosal lesions on the gingiva, palate, epiglottis, and arytenoid. The appearance showed both erosion and erosion with a white coating. Narrow band imaging clearly showed a white area at the site of the sub epithelial blisters and a mixed blue and brownish area at the site of the erosive area in which the mucosa was exfoliated without blistering. Narrow band imaging was therefore also useful for detecting blister lesions in mucous membrane pemphigoid because lesions were more clearly visible. Pharyngolaryngeal examination using optic fiberscopy should be performed in all mucous membrane pemphigoid patients.