Abstract
Inflammatory diseases of the oral mucosa can manifest themselves by various nosological processes of the oral cavity, but sometimes even against the background of pronounced inflammatory processes, stomatitis, gingivitis and many other diseases do not form, often this is due to systemic viral processes, for example, coronavirus infection. At the same time, clinical symptoms can be very diverse, or even absent even against the background of changes in the immune and microbial landscape of the oral cavity. With the progression of the disease, the process may spread to the palate, gums, palatine tonsils, larynx, and digestive tract. It is important to distinguish weakened individuals, individuals with immunodeficiency conditions who were on long-term use of antibacterial agents, corticosteroids and antineoplastic drugs. The persistence and recurrent nature of such inflammatory lesions requires not only the usual hygienic measures for the care of the oral cavity and teeth, but also appropriate justified therapy aimed at stimulating the protective forces of the oral mucosa.
Highlights
The oral cavity is anatomically and functionally connected with the pharynx, whose inflammatory diseases are currently in the focus of attention of otolaryngologists due to their wide prevalence, and mainly in people of working age
Cytokines are produced by lymphocytes and macrophages embedded in the epithelium of the mucous membrane, the source of cytokines in saliva is serum transudate and salivary glands
It is important to note that the content of cytokines in saliva does not correlate with their level in the blood, which indicates the autonomy of local immunity
Summary
The oral cavity is anatomically and functionally connected with the pharynx, whose inflammatory diseases are currently in the focus of attention of otolaryngologists due to their wide prevalence, and mainly in people of working age. These diseases are dangerous because they can cause the development of severe complications from the cardiovascular system, kidneys and joints. Most respiratory diseases are accompanied by damage to the pharyngeal mucosa and the lympho pharyngeal ring, which is part of the immune system and plays an important role in the formation of both local and general protective reactions of the body. To study the features of adaptive mechanisms of local immunity of the oral mucosa against the background of coronavirus infection and to justify the principles of immunocorrecting therapy based on the identified changes
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