Abstract
A 70-year-old Caucasian female presented with multiple small, firm, yellowish nodules in the mucosa of the lower and upper lips, buccal mucosa, and dorsal and ventral surfaces of the tongue. Medical history of the patient included carpal tunnel syndrome surgery, systemic arterial hypertension, osteoarthritis, osteoporosis, and hypercholesterolemia. Laboratory tests showed serum levels of thyroid-stimulating hormone (TSH) at 6.56 UI/µmL, leukocyte count of 3,400/mm³, and erythrocyte sedimentation rate of 36 mm/1 h. A biopsy of the oral lesions was performed, and the histopathologic examination revealed connective tissue with deposits compatible with amyloid material, which was also observed in the Congo red examination. Concurrently, chest radiograph, serum protein electrophoresis, C-reactive protein, urea and creatinine, and urinalysis were performed and did not reveal any alterations. The patient was referred to the rheumatologist and is now undergoing follow-up. A 70-year-old Caucasian female presented with multiple small, firm, yellowish nodules in the mucosa of the lower and upper lips, buccal mucosa, and dorsal and ventral surfaces of the tongue. Medical history of the patient included carpal tunnel syndrome surgery, systemic arterial hypertension, osteoarthritis, osteoporosis, and hypercholesterolemia. Laboratory tests showed serum levels of thyroid-stimulating hormone (TSH) at 6.56 UI/µmL, leukocyte count of 3,400/mm³, and erythrocyte sedimentation rate of 36 mm/1 h. A biopsy of the oral lesions was performed, and the histopathologic examination revealed connective tissue with deposits compatible with amyloid material, which was also observed in the Congo red examination. Concurrently, chest radiograph, serum protein electrophoresis, C-reactive protein, urea and creatinine, and urinalysis were performed and did not reveal any alterations. The patient was referred to the rheumatologist and is now undergoing follow-up.
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