Abstract
Isosorbide was introduced as an oral os motic diuretic in 1965. Two years later, Becker, Kolker, and Krupin demonstrated its ability to lower intraocular pressure in man. Subsequently, Barry, Khoury, and Brooks reported that isosorbide reduced the intraocular pressure in nine normal volun teers. Five additional reports in isosorbide and intraocular pressure appeared in the Japanese literature. This report presents our clinical experience with isosorbide in the management of various types of glaucoma.
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