Oral Involvement in a Case of Chronic Graft Versus Host Disease

Abstract

This article describes a case of oral involvement in chronic graft-versus-host disease (cGVHD) after hematopoietic cell transplantation. The patient suffered from painful oral ulcerations, especially on the tongue, lichenoid buccal mucosa lesions, and xerostomia. She also developed purpuric exanthema and scleroderma-like signs on her hands. Her history, in combination with clinical examination and histological findings of both lichenoid lesions and labial salivary glands, revealed cGVHD.