Abstract
Aim: The purpose of this meta-analysis was to evaluate the impact of oral health on quality of life in oral cancer patients (OCPs). Methods: PubMed, Scopus andWeb of Science databases were searched for publications on oral health-related quality of life (OHRQoL) in OCP and the information was extracted according to the PRISMA guidelines. A random effect model was used to obtain thepooled standard mean differences of Oral Health Impact Profile (OHIP)-14 questionnaire responsesin meta-analysis. Results: total of 12 research papers were analyzed andrevealed poor OHRQoL in OCPs (standard mean difference: 2.53; 95% CI: 1.55-3.50; p<0.00001) compared withhealthy individuals due to the effects of oncotherapy. Moreover, OHRQoL deterioratedwith combinations of different treatment modalities. Conclusion: Oral health and oncotherapy can affect the quality of life in OCPs.
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