Oral Giant Cell Angiofibroma: A Case Report

Abstract

Giant cell angiofibroma is a benign mesenchymal soft tissue tumour which commonly occurs in the orbital region, however is rare in the oral cavity. Microscopically, it is a well-circumscribed nonencapsulated mass containing multinucleate giant cells and many vascular spaces. It resembles solitary fibrous tumour (SFT) and may be part of the spectrum of SFT. Other histological differential diagnoses include giant cell fibroblastoma and dermatofibrosarcoma protuberans. As yet, 3 cases of giant cell angiofibroma occurring in the oral cavity have been reported in the English-language literature. We present a case of oral giant cell angiofibroma on the gingival area of lower left molars region in a 63 year old male with the multinucleate giant cells immunopositive with CD34.