Oral Findings of Children, Adolescents and Young Adults Affected by Muccopolysaccharidosis

Abstract

Objectives: Mucopolysaccharidosis (MPS) comprises of a set of rare inherited lysosomal disorder which results in deposition of glycosaminoglycans (GAGs) in various tissues and organs resulting in disturbances in the developing structures. The aim of the study was to systematically record the oral findings of patients diagnosed with MPS and subsequently assess their oral health needs. Methodology: A cross- sectional study was conducted on patients diagnosed with MPS (n=57). Complete soft tissue and hard tissue examination was done and the findings recorded. DMFT or def indices were recorded in accordance with WHO criteria and methods. Results: The study showed that the patients diagnosed with MPS have higher oral health care needs owing to the anatomical and pathological changes. The study showed that the patients diagnosed with MPS had poor oral hygiene and high caries incidence. However, the number of filled teeth in spite of high caries index wassignificantly less which showed neglected oral care. Interpretation and Conclusion: The patients diagnosed with MPS have higher oral health care needs. Hence, regular dental evaluation and treatment must be incorporated in their health care regimen.