Abstract

Oral exfoliative cytology is one of the easy, simple, economical and non-cumbersome diagnostic adjunct. It involves examining the exfoliated buccal cells for alterations in cellular and nuclear features. It offers the advantage of being useful in less resource setting areas. Though associated with many false results, the newer technological advancements have proven its diagnostic efficiency. Oral exfoliative cytology can readily be used as adjunct to disease diagnosis, however, it cannot replace biopsy.

Highlights

  • Exfoliative cytology is one of the most common diagnostic adjunct adapted in the disease diagnosis

  • With the success of cytology in cervical pathologies, it was adopted to other non cervical pathologies including oral lesions

  • It was used for studying various oral diseases, especially as an aid in the early detection of oral precancer and oral cancer [1]

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Summary

Introduction

Exfoliative cytology is one of the most common diagnostic adjunct adapted in the disease diagnosis. With the success of cytology in cervical pathologies, it was adopted to other non cervical pathologies including oral lesions It was used for studying various oral diseases, especially as an aid in the early detection of oral precancer and oral cancer [1]. Definition Exfoliative cytology is the microscopic examination of shed or desquamated cells from an epithelial surface. It is used as means of detecting malignancy and microbiologic changes and to measure hormonal levels. Such cells for examination can be obtained by scraping, aspiration, washing or smears. Studies have shown a sensitivity and specificity of 78.6-100% with these instruments [2,3,4,5,6]

Basis of exfoliative cytology
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