Abstract

Liver transplantation (LT) remains the only cure for hepatocellular carcinoma (HCC) in many cases. Over many years, most centers have applied the Milan criteria for selecting cirrhotic patients with HCC for LT. In a new era where several transplant groups are pushing the limits of transplanting HCC outside Milan criteria as an aggressive approach with promising results, we present interesting images of a patient that presented a unique and rare site of HCC metastasis after 36 months of liver transplantation.

Highlights

  • Over many years, most centers have applied the Milan selection criteria for cirrhotic patients with hepatocellular carcinoma (HCC)

  • We report here a case with an unusual site of tumor recurrence after liver transplantation (LT) that should be known as a potential site of metastasis

  • To the best of our knowledge, this is the first case of a metastatic HCC to the oral cavity after LT reported in English literature

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Summary

Introduction

Most centers have applied the Milan selection criteria for cirrhotic patients with hepatocellular carcinoma (HCC). Several groups from different countries have challenged these restrictive criteria with promising results [1]. This more aggressive approach could result in higher rates of tumor recurrence that should carefully be assessed in these patients with advanced HCC within the liver. We report here a case with an unusual site of tumor recurrence after liver transplantation (LT) that should be known as a potential site of metastasis

Case Report
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