Abstract

A 32 year old Indian male patient presented with chief complaints of a high fever, erythema on ear, severe polyarthritic joint pains & swelling, non pitting pedal oedema, facial puffiness and itching for past four days. He had no significant past medical and drug history and was serologically confirmed to have Chikungunya. Oral cavity inspection revealed whitish non erythematous pseudo membranous plaques on the hard palate, buccal surface of cheek and the floor of the mouth which was later microbiologically confirmed as Candidiasis. He tested negative for HIV and had leucopenia with severe CD4 T-lymphocytopenia. This is the first report of an opportunistic infection with CD4 T-lymphocytopaenia in Chikungunya fever.

Highlights

  • A 32 year old Indian male patient presented with chief complaints of a high fever, erythema on ear, severe polyarthritic joint pains & swelling, non pitting pedal oedema, facial puffiness and itching for past four days

  • The peripheral smear revealed lymphocytopenia, with the differential lymphocyte Count as 8%, among which 95% were identified as atypical lymphocytes with oval to round condensed nuclear fragments varying in number with toxic granules

  • The results showed HIV negative and CD4 lymphocytes of 260 cells/micro liter

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Summary

Introduction

A 32 year old Indian male patient presented with chief complaints of a high fever, erythema on ear, severe polyarthritic joint pains & swelling, non pitting pedal oedema, facial puffiness and itching for past four days. Case Report In May 2008, a 32 year old Indian male patient presented with chief complaints of a high fever with erythema on ear, severe polyarthritic joint pains & swelling, non pitting pedal oedema, facial puffiness and itching for four days in a Chikungunya viral epidemic outbreak declared region of South Canara district, Karnataka, India. He had no significant past medical and drug history.

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Conclusion

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