Abstract
The advancements made in biomaterials have an important impact on oral tissue engineering, especially on the bone regeneration process. Currently known as the gold standard in bone regeneration, grafting procedures can sometimes be successfully replaced by a biomaterial scaffold with proper characteristics. Whether natural or synthetic polymers, biomaterials can serve as potential scaffolds with major influences on cell adhesion, proliferation and differentiation. Continuous research has enabled the development of scaffolds that can be specifically designed to replace the targeted tissue through changes in their surface characteristics and the addition of growth factors and biomolecules. The progress in tissue engineering is incontestable and research shows promising contributions to the further development of this field. The present review aims to outline the progress in oral tissue engineering, the advantages of biomaterial scaffolds, their direct implication in the osteogenic process and future research directions.
Highlights
Both the hard and soft oral tissues play a crucial role in the development and maintenance of the main functions of the human body
The target of bone tissue engineering and regenerative medicine based on biomaterials is to develop proper scaffolds that can fulfill all the characteristics required by certain tissues in order to promote cell adhesion, proliferation, differentiation and angiogenesis
Due to the fact that the main property which qualifies a scaffold for bone tissue engineering is its biocompatibility, natural polymer-based scaffolds consisting in proteins, polysaccharides, minerals, growth factors, etc., and the interaction between scaffolds and cells, have to be considered in the first place
Summary
Both the hard and soft oral tissues play a crucial role in the development and maintenance of the main functions of the human body. Several biomaterials have successfully contributed to the compensation of functional loss These biomaterials have similar characteristics to the replaced tissue (corrosion rate, biocompatibility, non-toxicity, specific degradation rate). The development of tissue engineering technologies has achieved its goal regarding the implementation of novel approaches and alternatives of biomaterials in order to replace the oral tissue. This multidisciplinary approach is based on several. The characteristics of biomaterial scaffolds provided the possibility of enhancing their chemical and biological properties, influencing cell adhesion, proliferation and differentiation. The dentistry field currently benefits from several alternatives for the oral soft and hard tissue regeneration management, successfully improving treatment and surgical outcomes
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
