Abstract
Oral rabies vaccination (ORV) can increase rabies vaccination coverage among dogs that are inaccessible to parenteral vaccination (i.e., inaccessible dogs). Because bait uptake can differ according to the bait attractant used and dog characteristics, we evaluated proportion of bait uptake and time to bait uptake using three bait formulations. We looked for associations between bait uptake and dog characteristics (temperament, age, and body condition) and assessed the efficiency of using these bait formulations, as measured by number of dogs vaccinated per hour.A total of 356 baits were offered to free roaming dogs in urban and peri-urban districts of Bangladesh. Fish baits were ignored by 86% (n = 122; 95% CI: 79–91%) of dogs, whereas 60% (n = 45; 95% CI: 49–70%) consumed egg baits and 89% (n = 124; 95% CI: 83–93%) consumed intestine baits. Among the consumed baits, dogs fully consumed 56% (n = 10; 95% CI: 34–75%) of fish baits, 84% (n = 38; 95% CI: 71–92%) of egg baits, and 98% (n = 122; 95% CI: 94–100%) of intestine baits. Among inaccessible dogs, no associations were found between bait uptake and dog characteristics in either bivariate or multivariate analyses. Bait consumption averaged 2 dogs per hour for fish baits, 10 dogs per hour for egg baits, and 18 dogs per hour for intestine baits.The absence of association between bait type preference and individual dog characteristics simplifies the process of choosing attractants for oral rabies vaccines. While intestine attractants achieved highest uptake, egg baits may prove a suitable compromise when considering biological and operational constraints. The efficiency of ORV was demonstrated when compared to parenteral vaccination of free-roaming dogs previously described.
Highlights
Following the successful use of oral rabies vaccines in the elimination of sylvatic fox rabies in western Europe [13], and fox and coyote rabies virus variants from the southern United States [12], oral rabies vaccination (ORV) has been proposed as a complemen-⇑ Corresponding author at: Poxvirus and Rabies Branch, DHCPP, CDC, 1600 Clifton tary method for the elimination of canine rabies [18]
ORV is well suited for vaccinating dogs that are inaccessible to parenteral vaccination, or for which parenteral vaccination using capturevaccinate-release (CVR) requires disproportionate resources to achieve the 70% vaccination coverage necessary to eliminate canine rabies
Fish baits were ignored by 86% (n = 122; 95% CI: 79–91%) of dogs, whereas 60% (n = 45; 95% CI: 49–70%) consumed the egg baits and 89% (n = 124; 95% CI: 83–93%) consumed the intestine baits (Fig. 3)
Summary
Following the successful use of oral rabies vaccines in the elimination of sylvatic fox rabies in western Europe [13], and fox and coyote rabies virus variants from the southern United States [12], oral rabies vaccination (ORV) has been proposed as a complemen-. ⇑ Corresponding author at: Poxvirus and Rabies Branch, DHCPP, CDC, 1600 Clifton tary method for the elimination of canine rabies [18]. ORV is well suited for vaccinating dogs that are inaccessible to parenteral vaccination (e.g., free-roaming owned dogs and feral dogs), or for which parenteral vaccination using capturevaccinate-release (CVR) requires disproportionate resources to achieve the 70% vaccination coverage necessary to eliminate canine rabies.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
