Abstract
To reduce the of risk infection after colorectal surgery, oral antibiotic preparation (OAP) and mechanical bowel preparation (MBP) can be applied. Whether OAP can be used without MBP is unclear. A meta-analysis of observational studies demonstrated comparable effectiveness of OAP with and without MBP regarding SSI risk.
Highlights
A single-center randomized controlled trials (RCTs) from Israel found no difference between oral antibiotic preparation (OAP) and OAP combined with mechanical bowel preparation (MBP) regarding Surgical site infection (SSI) risk, suggesting that the MBP component can be safely omitted.[19]
SSI risk was significantly reduced when patients received either OAP only or OAP combined with MBP
We demonstrated that the impact of MBP with OAP is similar to that of OAP alone
Summary
We aimed to provide insight into the effectiveness of OAP without MBP on SSI risk using data from observational studies. Because we aimed to reduce confounding bias, we extracted the adjusted odds ratios and 95% confidence intervals (CIs)
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