Abstract
Aim: With regard to the prevalence of Multiple Sclerosis and the importance of early diagnosis, we aimed to assess the prevalence of oral and facial manifestations in patients with multiple sclerosis (MS). Material and Methods: This cross-sectional study assessed 400 MS patients for oral and facial manifestations. Trigeminal neuralgia, dysarthria, dysphagia, TMD, facial palsy and visual symptoms were documented. Occurrence of each manifestation was determined, its confidence interval was evaluated within a probability of 95%, and the role of the related factors in this prevalence was analyzed with the Chi-square test. Results: This study of 400 patients with MS revealed that 89.2% demonstrated oral and facial symptoms. The most frequent manifestations were visual symptoms (79.5%), dysarthria (44.3%), dysphagia (21%), facial palsy (15.3%), temporomandibular disorder (14.3%) and trigeminal neuralgia (13.3%). The related factors (individual and familial) showed no significant relation to the incidence of these manifestations. Conclusion: This study revealed a high prevalence of oral and facial manifestations in MS patients and therefore the dentist may be the first to diagnose this.
Highlights
This study revealed a high prevalence of oral and facial manifestations in multiple sclerosis (MS) patients and the dentist may be the first to diagnose this
The high prevalence of multiple sclerosis (MS) in the northern hemisphere is of concern [1]
Six oral and facial disorders upon which patients have studied by neurologist were Trigeminal Neuralgia, Facial Palsy, TMD (Temporomandibular disorder), Dysphagia, Dysarthria and Visual
Summary
The high prevalence of multiple sclerosis (MS) in the northern hemisphere is of concern [1]. In this disease, discrete plaques of demyelization occur at sites throughout the CNS causes by a cellmediated immune response [2]. Discrete plaques of demyelization occur at sites throughout the CNS causes by a cellmediated immune response [2] This chronic inflammatory disease is often progressive and attacks the myelin sheath of the CNS. MS is a destructive disease that affects the oral and maxillofacial complex as well. Oral and facial manifestation in MS patients, are significant for dentists especially trigeminal neuralgia (TN), trigeminal sensory neuropathy (TSN) and facial palsy (FP) [1]. As the prevalence of oral and facial manifestation in MS is high, the probability of MS can be raised, and preclude unnecessary treatment of these manifestations instead of the primary etiology [3]
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