Abstract
People receiving amiodarone had a lower incidence of atrial tachyarrhythmias compared to controls (16.1% vs. 29.5%, hazard ratio 0.52, 95% CI 0.34 to 0.69, po0.001). This trend was sustained in people younger than 65 years, in people older than 65 years, in people who had CABG surgery alone, in people who had valve replacement or repair with or without CABG, in people who received preoperative beta-blockers, and in people who did not receive preoperative beta-blockers. People receiving amiodarone were more likely than controls to have their dosage reduced (11.4% vs 5.3%, p 1⁄4 0.008). There were no significant differences between groups in serious postoperative complications, in-hospital mortality, readmission within six months, or one-year mortality.
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