Oral Administration of a Novel Small Molecule Blocks the BMP Canonical and the Non-canonical BMP2, BMP4, and BMP5 Signaling Pathways Ameliorates EAE Through Oligodendrogenesis Remyelination and Preservation of Axonal Integrity and Reduces Astrogenesis (P7-6.015)

Maya Golan,Ehud Marom,Nadav Bleich Kimelman,Karin Fainberg,Moshe Benhamou,Shai Rubnov,Arnon Karni,Uri Danon

doi:10.1212/wnl.0000000000206159

Oral Administration of a Novel Small Molecule Blocks the BMP Canonical and the Non-canonical BMP2, BMP4, and BMP5 Signaling Pathways Ameliorates EAE Through Oligodendrogenesis Remyelination and Preservation of Axonal Integrity and Reduces Astrogenesis (P7-6.015)

Maya Golan, Ehud Marom + Show 6 more

https://doi.org/10.1212/wnl.0000000000206159

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Journal: Neurology

Publication Date: Apr 9, 2024

#BMP2 Signaling Pathways #Non-canonical Signaling Pathways + Show 8 more

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Abstract

Oral Administration of a Novel Small Molecule Blocks the BMP Canonical and the Non-canonical BMP2, BMP4, and BMP5 Signaling Pathways Ameliorates EAE Through Oligodendrogenesis Remyelination and Preservation of Axonal Integrity and Reduces Astrogenesis (P7-6.015)

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