OR54. Relationship Between Degree of Smoking Based on the Brinkman Index and Mean Tunica Intima-Media Thickness of the Carotid Artery (CIMT) in Young Adult Patients in H. Badaruddin Kasim Tabalong Regional Hospital, South Kalimantan

Abstract

Abstract Background and Aims This study is to analyse the relationship between the degree of smoking based on the Brinkman Index and mean carotid intima-media thickness (CIMT) in young adult patients in H Badaruddin Kasim Tabalong Hospital. Method and Results This cross-sectional study included 38 patients undergoing medical check-up. The smoking degree was measured at the time of the medical checkup in H Badruddin Kasim Tabalong Hospital between February April March 2019. The subjects were categorised into three groups based on the Brinkman Index, mild smokers (n = 19), moderate smokers (n = 19), and there was no patient in the heavy smoker group (n = 0), according to their responses to a questionnaire. We compared the CIMT in the three groups after adjusting for age. CIMT was measured using doppler ultrasound. The analysis used by Pearson correlation and independent samples test (t-test). Multivariate analysis performed using linear regression. In both right and left carotid artery assessment, carotid intima-media thickness was significantly increased in moderate smoker group (p = 0.008 and p = 0.013, respectively). There was a significant positive correlation between Brinkman Index and carotid intima-media thickness (p = 0.08, r = 0.425). The smoking period was significantly associated with carotid intima-media thickness in both right and left carotid artery (p = 0.001, p = 0.013, respectively). There was no significant association between the number of cigarettes consumed and carotid intima-media thickness. Conclusion The Brinkman Index is positively correlated with mean carotid intima-media thickness.