OQAS를 이용한 중심장액성맥락망막병증의 광학적 질 분석

Abstract

목적: 중심장액성맥락망막병증을 치료 중인 눈과 완치된 눈의 광학적 질의 변화를 알아보았다. 방법: 총 68명 136안을 대상으로 중심장액성맥락망막병증을 치료 중인 눈 및 무증상 반대편 눈, 중심장액성맥락망막병증을 진단받은 후 완치된 눈 및 반대편 눈과 정상인 눈의 객관적 산란지수, 변조전달함수 값, 상의 집속률, 점상강도 분포함수 50%폭과 10% 폭 및 대비감도를 측정하여 분석하였다. 결과: 중심장액성맥락망막병증을 치료 중인 눈은 반대편 무증상 눈, 질환이 완치된 눈 및 정상 눈과 비교하여 모든 광학적 질 평가에서 통계적으로 유의하게 광학적 질의 저하가 나타났다. 중심장액성맥락망막병증을 치료 중인 반대편 무증상 눈과 완치된 눈의 경우는 통계적으로 유의하지는 않았지만 정상안보다 광학적 질의 저하 경향이 나타났다. 결론: 본 연구를 통하여 중심장액성맥락망막병증 치료 단계에 따라 광학적인 질에 차이가 있음을 밝혔으며, 중심장액성맥락망막병증의 완치 판정 및 예후 평가에서 광학적 질의 평가의 활용을 제안한다. Purpose: The present study was aimed to investigate the change of optical quality in fully cured eyes from central serous chorioretionopathy(CSC) and CSC under treatment, respectively. Methods: A total of 136 eyes(68 subjects) was divided into CMC under treatment and its asymptomatic contralateral eye, fully cured eyes after being diagnosed with CMC and its contralateral eye, and normal eyes. Objective scattering index, cut-off value in modulation transfer function, focusing rate, PSF(Point Spread Function) width at 50%, 10% and the contrast sensitivity were measured and analyzed. Results: CMC under treatment showed statistically significant decrease in all evaluations of optical quality compared with asymptomatic contralateral eyes, fully cured eyes and normal eyes. Although there was no significant difference in optical quality between asymptomatic contralateral eyes of CMC under treatment and fully cured eyes, there was tendence in optical quality decreasing compared with normal eyes. Conclusions: From the study, it was revealed that the optical quality was different according to the treatment phase in CMC. The use of optical quality assessment for the decision of complete cure and the evaluation of prognosis in CMC is also proposed.