Abstract
The cavitation bubbles in water generated by laser irradiated Au nanoparticles (NPs) exhibit potential applications in the photothermal therapy and enhancing photoacoustic imaging. The exploration of the related processes is crucial to improve the opto-acoustic efficiency that is important to these applications. Herein a model including the Mie theory, gas state equation, Rayleigh-Plesset equation, and sound pressure equation is established. Through this model, the optimal diameter of an Au NP, the threshold value of the laser induced cavitation, the time varying volume and pressure of the bubble is obtained. The influences of laser flux and NP diameter to the volume and pressure of the bubble are simulated based on this model. The acoustic pressure of many Au NPs is obtained through the superposition of the opto-acoustic wave of a single Au NP, in which the Au NPs are assumed to be distributed randomly in the laser irradiation area. The opto-acoustic wave of many Au NPs is also investigated experimentally, which coincides with the theoretical analyses.
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