Optimum Conditions for Enhanced Production of Podophyllotoxin from Penicillium sp. Isolated from Khanspur, Pakistan

Umar Farooq Gohar,Attia Majeed,Bushra Muneer,Hamid Mukhtar

doi:10.17582/journal.pjz/20210401130420

Abstract

Optimum Conditions for Enhanced Production of Podophyllotoxin from Penicillium sp. Isolated from Khanspur, Pakistan

Highlights

The objective of this study was to observe the effects of low-molecular-weight heparin calcium (LMWHC) combined with argatroban on the treatment, vascular endothelial function, inflammatory factors and neurological function in patient with acute cerebral infarction
Recent years witnessed its investigates the actual efficacy of low-molecular-weight occurrence in younger population. It can occur at any heparin calcium (LMWHC) combined with argatroban in age with no specific morbidity group, and there is no the treatment of ACI, and determines the basic mechanism forewarning at the time of onset
It does not affect vascular permeability when it exists in the form of calcium salt, and can play a role in improving cerebral hemodynamics and producing antithrombotic effects, but it is not ideal for the treatment of progressive cerebral infarction when used alone, so its combined use with other anticoagulant drugs in clinical application is currently the main treatment strategy (Arahata and Asakura, 2018; Zhu et al, 2018)

Summary

Introduction

The objective of this study was to observe the effects of low-molecular-weight heparin calcium (LMWHC) combined with argatroban on the treatment, vascular endothelial function, inflammatory factors and neurological function in patient with acute cerebral infarction. We conclude that LMWHC combined with argatroban are safe and effective in the treatment of acute cerebral infarction. Authors’ Contribution X Yao and GZ collected the samples, conducted the experiments and analysed the results. Recent years witnessed its investigates the actual efficacy of low-molecular-weight occurrence in younger population. It can occur at any heparin calcium (LMWHC) combined with argatroban in age with no specific morbidity group, and there is no the treatment of ACI, and determines the basic mechanism forewarning at the time of onset. Days of treatment, intravenous infusion of 10mg argatroban was given, 2 times a day and 3 h per time

Objectives

Results

Conclusion