Abstract

According to the statistics of the Ministry of Health of Ukraine, a significant number of women in Ukraine terminate their pregnancies every year: 60% of them due to unwanted pregnancy and 40% - for medical reasons. The introduction of various modern methods of contraception, unfortunately, does not lead to a decrease in the frequency of abortions, and it remains quite high in our country today. The share of medical termination of pregnancy in different regions of Ukraine is 08-1.5% of the total number of abortions. It is the quality of medical care for short-term medical abortion that should be effective, affordable, patient-oriented, fair and safe, which contributes to increasing the availability of this method.
 The purpose of the study is to investigate the effectiveness of the use of desaminooxytocin during medical termination of pregnancy in order to prevent early complications associated with the delay in the expulsion of elements of the fetal egg from the uterine cavity.
 Research materials and methods. 170 women with a gestation period of 4+0 - 6+6 weeks were under supervision. For termination of pregnancy, each woman received 200 μg of mifepristone once (in the presence of a doctor), and later (after 21-24 hours) transbuccally 400 μg of misoprostol. A day after the procedure, a control ultrasound was performed. In order to complete and accelerate the evacuation of the contents of the uterine cavity, demoxytocinum in a dose of 50 IU (1 tablet) was administered transbuccally 4-6 times with an interval of every 2-3 hours.
 The results. After using demoxytocinum in a dose of 2-3 tablets, 18 (10.6%) women had a complete evacuation of the elements of the fetal egg, in 2 (2.2%) – it was necessary to increase the dosage to 4-5 tablets, in 3 (1.8 %) - the dose was increased to 6 tablets. No significant difference was noted in repeated and primary pregnancies, no differences were noted depending on the age of the woman and the term of pregnancy.
 Conclusions. The use of demoxytocinum during medical termination of pregnancy for the purpose of prevention of early complications associated with the delay in the expulsion of elements of the fetal egg from the uterine cavity is highly effective. Efficiency in the study was 97.8%.

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