Abstract

Aim: to study the effectiveness of different treatment options for male hypogonadism. Material and methods: the paper investigates outcomes in treating male hypogonadism (86 patients with secondary male hypogonadism). Scientific literature was reviewed to single out the following methods: androgen replacement therapy subcutaneous testosterone pellet implants use of long-acting subcutaneous testosterone tablets (the use of subcutaneous long-acting testosterone tablets as replacement therapy), a combination of traction therapy and medication Testosterone undecanoate. Results: androgen replacement therapy promotes the development of a number of beneficial effects in terms of physique, metabolic control, psychological and sexual indicators. The use of long-acting subcutaneous testosterone pellets can enhance the androgenic effect at the receptor level. The combined method of treatment traction therapy and medication Testosterone undecanoate is relevant for men with concomitant micropenia. The surgical method of subcutaneous testosterone pellet implants is recommended for patients with contraindications to testosterone replacement therapy. The determination of sexual constitution’s indicators testified to persistent sexual rehabilitation in the long term after transplantation of testicle. Conclusions: Each clinical case should be approached individually and optimized in case of concomitant pathologies. According to the scientific literature, androgen replacement therapy is optimized as an application of long-acting subcutaneous testosterone tablets, which shows good results in case of concomitant pathologies. For men with concomitant micropenia, it is suggested to apply the combined treatment of traction therapy and medication Testosterone undecanoate. In case of contraindication to hormone therapy, subcutaneous testosterone pellet implants are the optimal option.

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