Abstract
In this paper, we propose a practical optimized phase-sensitive inversion recovery approach for longitudinal contrast enhancement of tissues. With the usage of double dynamic range of longitudinal magnetization, the contrast of tissues can be maximized with an optimal inversion pulse, which is optimized by an extended version of optimal-control-based gradient ascent method. Moreover, to demonstrate this optimized contrast, a modified image reconstruction of region-growing spin reversal operation is presented. Simulation experiments show that even for tissues with same \(T_{1}\) value, the contrast can be increased up to 28 \(\%\) compared with the saturation contrast enhancement. It has a great potential for enhancing contrast of tissues, and in particular, of limited intrinsic different tissues.
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