Abstract
Kleeb Bua Daeng formula is one of the popular remedies sold in Chao Phya Abhaibhubejhr Hospital, Thailand. This formula contains Piper nigrum L., Nelumbo nucifera Gaertn., and Centella asiatica L. as active components. Owing to getting the highest content of its phytochemical compounds, the conditions of solvent extraction for this formula were optimized. The type of solvent, number of extraction times, and ratio between the material and solvent were varied in this study using the Box–Behnken design. The important phytochemical constituents (total phenolics, flavonoids, carotenoids, and anthocyanins) were also determined. From the result of this study, it was found that the highest content of each total active compound was obtained from different conditions such as the optimal extraction condition of phenolic content was obtained using methanol as solvent, one time of extraction, and the ratio of powder and solvent was 1 : 6. Thus, the variation of solvent extraction condition could affect the phytochemical content. Further studies about the herbal formula involving the extraction process should concern the variation of extraction conditions to get the highest content of the active compound.
Highlights
Kleeb Bua Daeng formula (KBD) is one of the ai traditional herbal formula products by Chao Phya Abhaibhubejhr Hospital, Prachinburi Province, ailand. ree main components are Piper nigrum L. fruit, Nelumbo nucifera Gaertn. petal, and Centella asiatica L. leaf. is product was claimed to help insomnia improvement and support memory
Centella asiatica L. (CA) known as Kotu Gola is medicinal plant in family Apiaceae commonly used in the treatment of wound healing and as an anti-inflammatory, antioxidant, and neuroprotective agent [18,19,20,21]. e active constituents found in the aerial part are asiaticoside, polyphenols, flavonoids, and carotenoids [22, 23]
Materials and Equipment. ai Traditional herbal formula used in this study is the KBD Formula, which contains 3 herbs: Centella asiatica L. leaf, Nelumbo nucifera Gaertn. petal, and Piper nigrum L. fruit, and their voucher specimens were deposited at the Chao Phya
Summary
Kleeb Bua Daeng formula (KBD) is one of the ai traditional herbal formula products by Chao Phya Abhaibhubejhr Hospital, Prachinburi Province, ailand. ree main components are Piper nigrum L. fruit, Nelumbo nucifera Gaertn. petal, and Centella asiatica L. leaf. is product was claimed to help insomnia improvement and support memory. Ree main components are Piper nigrum L. fruit, Nelumbo nucifera Gaertn. Pharmacological activities of Piper nigrum fruit were reviewed such as anticancer, antidepressant, anti-inflammatory, analgesic, antioxidant, and antimicrobial [1,2,3,4,5]. (NN) is an aquatic plant in family Nelumbonaceae Various parts of this plant has been reported and used for the anti-inflammatory, antioxidant, neuroprotective, anticancer, and antibacterial activities [7,8,9,10,11,12]. (CA) known as Kotu Gola is medicinal plant in family Apiaceae commonly used in the treatment of wound healing and as an anti-inflammatory, antioxidant, and neuroprotective agent [18,19,20,21]. Many techniques can be used for the extraction of the active component in herbal remedy or herbal plant such as solvent extraction, ultrasound-assisted extraction, microwave-assisted extraction, and supercritical
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
