Abstract
Ultrafast (UF) 2D NMR, which enables the acquisition of 2D spectra within a single scan, is nowadays used in a large array of applications. However, the use of UF-HSQC experiments is still limited by the need to compromise between spectral widths and resolution. Interleaved acquisitions can overcome this limitation, albeit at the cost of strong artifacts. We show that the occurrence of these artifacts is mainly related to the discontinuous decoupling scheme which is generally used in UF-HSQC. In this paper, four continuous decoupling schemes using adiabatic pulses are optimized for this kind of experiments, giving access to full-range UF-HSQC spectra.
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