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Abstract
Konjac glucomannan (KGM) is a polysaccharide extracted from Amorphophallus konjac, and its degradation product is konjac oligo‐glucomannan (KOG). The aim of this study was to produce KOG from KGM and to evaluate its effect on the gut microbiota in fecal batch culture. KOG was produced by enzymatic hydrolysis using β‐mannanase. The optimum conditions were as follows: reaction temperature of 48°C, reaction time of 4 hr, pH of 5.5 and E/S of 0.05% followed by purification step using 3,000 NMWC ultrafiltration (UF) membrane pore size. The effect of KOG on changes in human fecal bacterial populations and short‐chain fatty acids (SCFAs) production was evaluated. The results showed that low‐molecular weight KOG (LKOG) from purification step with concentration of 9.54 mg/ml, and a prebiotic index (PI) of 0.76 was successfully produced. LKOG can enhance the production of butyric acid in the colon with the highest concentration (8.24 mM) found at 72 hr fermentation.
Highlights
Sources of prebiotic can be found in most part of the world but not in Asia
Konjac glucomannan (KGM) is a polysaccharide derived from A. konjac which is mainly composed of mannose, and glucose is found in abundance in Asia Southeast Asia (Tester & Al-Ghazzewi, 2017)
konjac oligo-glucomannan (KOG) was produced by enzymatic hydrolysis of KGM using β-mannanase
Summary
Sources of prebiotic can be found in most part of the world but not in Asia. Konjac glucomannan (KGM) is a polysaccharide derived from A. konjac which is mainly composed of mannose, and glucose is found in abundance in Asia Southeast Asia (Tester & Al-Ghazzewi, 2017). KGM has been used as emulsifier, thickener, or as nutritional supplements for constipation, high cholesterol and obesity patients (Behera & Ray, 2016). Human studies with glucomannan as dietary supplement have shown that glucomannan can promote weight loss in obesity patients and has the capability to reduce the risk of cancer and LDL cholesterol (Connolly et al, 2010) and selectively promote the growth of good bacteria in the gut so can act as prebiotic (Al-Ghazzewi, Khanna, Tester, & Piggott, 2007)
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