Abstract
This is the first study on ultrasound-assisted extraction (UAE) of bioactive compounds from different types of tobacco industry wastes (scrap, dust, and midrib). The obtained results were compared with starting raw material (tobacco leaves) to see the changes in bioactive compounds during tobacco processing. Results suggested that tobacco waste extracts possess antioxidant activity and considerable amounts of targeted bioactive compounds (phenolics and solanesol). The content of chlorogenic acid varied between 3.64 and 804.2 μg/mL, caffeic acid between 2.34 and 10.8 μg/mL, rutin between 11.56 and 93.7 μg/mL, and solanesol between 294.9 and 598.9 μg/mL for waste and leaf extracts, respectively. There were noticeable differences between bioactive compounds content and antioxidant activity in extracts related to applied UAE conditions and the used type of tobacco waste. Results show that optimal UAE parameters obtained by response surface methodology (RSM) were different for each type of material, so process optimization proved to be necessary. Considering that tobacco waste is mostly discarded or not effectively utilized, the results clearly show that tobacco waste could be used as a potential source of some bioactive compounds.
Highlights
Tobacco is the most widely cultivated plant in the world which is not consumed as food
Taking into account the numerous advantages of ultrasound-assisted extraction (UAE), such as reduced extraction time, lower temperature, and acceptable solvent consumption, this method should be considered as an effective alternative method for the extraction of solanesol and phenolic compounds from tobacco wastes
To the best of our knowledge, this is the first study which looked into extraction and composition of bioactive compounds in different types of tobacco wastes using UAE
Summary
Tobacco is the most widely cultivated plant in the world which is not consumed as food. Leaves are the most valuable part of tobacco plant and other parts like stem, root, midrib are considered as a waste. Tobacco is part of Solanaceae family such as potatoes and tomatoes [1]. Tobacco can be used as a valuable source of bioactive compounds, which could be recovered and used in cosmetics, perfumes and pharmaceuticals [2]. Interest in bioactive compounds extracted from tobacco and tobacco waste increased over the past years [3]. As a result of that growing interest, ultrasound-assisted extraction (UAE) has been widely used for the extraction of bioactive compounds from tobacco leaves (Table 1)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
