Optimization of Treatment in Patients with Second-to-Third Degree Thermal Burns

Abstract

Objective: to study the time course of changes in the values of intoxication and leukocyte phagocytic activity in patients with second-to-third degree burns with a Klinitron unit being included into the standard therapy regimen. Subjects and methods. Twenty-six patients with second-to-third degree thermal burns were examined and treated, by determining the degree of burn injury from the Frank index, the level of endotoxicosis and leukocyte phagocytic activity. Results. The incorporation of the Klinitron unit into the complex of intensive therapy in the burnt results in a reduction in the level of intoxication and favors normalization of leukocyte phagocytic activity, which lowers the likelihood of developing infectious and toxic complications of burn disease and reduces the length of intensive care unit stay. Conclusion. The use of the Klinitron unit in the complex of the standard intensive care regimen contributes to prompter scab drying, ensures temperature comfort and the maximum low contact pressure on wounds, improves conditions for engrafting the transplanted skin flaps and wound epithelization, reduces the severity of endotoxicosis, and enhances the nonspecific resistance of the organism (phagocytic activation). Key words: thermal burns, intoxication, Klinitron, nonspecific resistance.