Abstract

Purpose: To evaluate the effect of axial length (AL) and the average preoperative keratometry (K) on the A constant in the SRK/T formula. Methods: The retrospective, comparative case series includes 635 eyes from 407 cataract patients from Columbia University Medical Center from January 2006 to August 2010, operated by a single surgeon using a temporal incision and the Acrysof SN60WF IOL (Alcon Laboratories, TX). Using the postoperative manifest refraction and biometry data, we calculated the precise A constant (Ap) necessary to yield the postoperative spherical equivalent for each eye. To optimize the A constant, we developed three regression models (linear, quadratic, and categorical in 7 AL groups) to relate these precise A constants to AL and K. We verified our method with another series of 45 eyes for which we calculated mean errors (defined as the difference between the spherical equivalent of the postoperative refraction and the predicted postoperative refraction) using the optimized and manufacturer’s suggested A constants. Results: There is a statistically significant relationship between AL (P < 0.001), K (P < 0.001) and the A constant. Ap increased as AL increased and as K decreased. In the validation data set, optimizing the A constant reduced mean errors from 0.50 D to 0.25 D and also reduced hyperopic refractive outcomes. Conclusions: The A constant for longer eyes with flatter corneas is larger than the A constant for shorter eyes with steeper corneas. Optimizing A constants using both AL and K improved the predictability of refractive outcomes without modification to the SRK/T formula.

Highlights

  • IntroductionIn small incision cataract surgery, an accurate refractive outcome depends on a reliable intraocular lens (IOL)

  • In small incision cataract surgery, an accurate refractive outcome depends on a reliable intraocular lens (IOL)How to cite this paper: Merriam, J.C., Nong, E., Zheng, L. and Stohl, M. (2015) Optimization of the A Constant for the SRK/T Formula

  • This study examines the effect of axial length (AL) and average preoperative keratometry (K) on the A constant using a large cohort of cataract surgery patients and the Acrysof SN60WF IOL

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Summary

Introduction

In small incision cataract surgery, an accurate refractive outcome depends on a reliable intraocular lens (IOL). (2015) Optimization of the A Constant for the SRK/T Formula. Refinement of the constants of the IOL formulas may help to achieve the targeted refraction [2]-[4]. Sheard and colleagues [8] reported that at the extremes of AL and K, the SRK/T was less accurate in calculating the corrected AL and corneal height, leading to inaccuracies in the IOL power prediction. Eom and colleagues showed that using A constants adjusted for corneal power improved refractive outcomes [9]. Our results suggest the use of these optimized A constants can improve the accuracy of the predicted postoperative refraction

Methods
The Models to Optimize the A Constant
Validating the Models
Validating

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