Abstract
Aims: The aim of this study is optimization of the concentrations of carbon and nitrogen sources for lipase production by Rhizopus arrhizus using response surface methodology . Study Design: For this work optimal 2 2 composite design was used for studying the optimal concentrations of corn starch and tryptone for lipase production by submerged fermentation. A series of planned experiments in three replications was carried out and a mathematical model was developed which was used to describe the process. Optimal levels of studied independent variables were calculated by using the model and the conversion rate. Place and Duration of Study: This study is a part of PhD dissertation developed in University of
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