Optimization of nanofiber diameter in the electrospinning of polyamide 6 by two-level factorial design

Abstract

The utilization of 2-level factorial design has been extensive in the literature to observe the relationship between parameters and responses. Among the subjects open for exploration, the process of nanofiber creation stands out as an intriguing avenue to explore the correlations that emerge between variables and outcomes. The primary objective of the study is to establish the relationships between the parameters of electrospinning of polyamide 6 (PA6) solutions to obtain desired nanofiber diameters by response surface method (RSM) and two level full factorial design. The investigation hones in on four critical parameters related to the electrospinning of PA6 solutions. These parameters encompass factors like solution concentration, applied voltage, distance between the spinneret and the collector, and the flow rate of the solution. Employing a two-level factorial design, these parameters are methodically manipulated at two distinct levels each to systematically unravel their individual and collective impacts on nanofiber diameter outcomes. To understand the relationship between electrospinning process and these factors, these kind of experimental studies gives us much accurate results.