Optimization of matrix solid phase dispersion method for quantification of pretilachlor in soil and rice

Abstract

A novel and simple sample preparation method viz. Matrix Solid Phase Dispersion (MSPD) method was compared with traditional Liquid-Solid Extraction (LSE) method for determination of pretilachlor residues in soil and rice samples. The determination of analyte was carried out using High Performance Liquid Chromatography equipped with UV/visible detector. Several extraction parameters of MSPD such as type of dispersion sorbent, type and volume of elution solvent and sample to sorbent mass ratio were investigated. Under the optimal conditions, mean recoveries of pretilachlor from soil and rice grain were in the range of 92.8–101.6 percent and 80.8–90.9 percent, respectively, with relative standard deviations below 10 percent. Linearity for pretilachlor was in the concentration range of 0.01–10 μg g−1 with correlation coefficient (R2) = 0.998. The limit of detection and limit of qualification were 0.003 μg g−1 and 0.01 μg g−1, respectively. MSPD extraction has been found as an efficient method due to better extraction efficiency.